APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN

APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN

Introduction: IgA nephropathy (IgAN) is the most common disease leading to end-stage renal disease, and tubular fibrosis represents an important risk factor for disease progression. However, research on early molecular diagnostic indicators of tubular fibrosis and the mechanisms underlying disease p...

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Bibliographic Details
Main Authors: Kuipeng Yu, Lin Ding, Xin An, Yanjiang Yang, Xiaoning Zhang, Luyao Li, Chunjie Wang, Fang Bai, Xiangdong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
APOC1
IgAN
biomarker
NK-κB
machine learning algorithms
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1181435/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1181435/full

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