Irisin stimulates protective signaling pathways in rat hippocampal neurons

Irisin stimulates protective signaling pathways in rat hippocampal neurons

Physical exercise stimulates neuroprotective pathways, has pro-cognitive actions, and alleviates memory impairment in Alzheimer’s disease (AD). Irisin is an exercise-linked hormone produced by cleavage of fibronectin type III domain containing protein 5 (FNDC5) in skeletal muscle, brain and other ti...

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Bibliographic Details
Main Authors: Mychael V. Lourenco, Guilherme B. de Freitas, Ícaro Raony, Sergio T. Ferreira, Fernanda G. De Felice
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
FNDC5/irisin
Alzheimer’s disease
hippocampus
reactive oxygen species (ROS)
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.953991/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2022.953991/full

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