Irisin stimulates protective signaling pathways in rat hippocampal neurons

Irisin stimulates protective signaling pathways in rat hippocampal neurons

Physical exercise stimulates neuroprotective pathways, has pro-cognitive actions, and alleviates memory impairment in Alzheimer’s disease (AD). Irisin is an exercise-linked hormone produced by cleavage of fibronectin type III domain containing protein 5 (FNDC5) in skeletal muscle, brain and other ti...

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Bibliographic Details
Main Authors:	Mychael V. Lourenco, Guilherme B. de Freitas, Ícaro Raony, Sergio T. Ferreira, Fernanda G. De Felice
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	FNDC5/irisin Alzheimer’s disease hippocampus reactive oxygen species (ROS) gene expression
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2022.953991/full

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