An overview of the past decade of bufalin in the treatment of refractory and drug-resistant cancers: current status, challenges, and future perspectives

An overview of the past decade of bufalin in the treatment of refractory and drug-resistant cancers: current status, challenges, and future perspectives

Profound progress has been made in cancer treatment in the past three decades. However, drug resistance remains prevalent and a critical challenge. Drug resistance can be attributed to oncogenes mutations, activated defensive mechanisms, ATP-bind cassette transporters overexpression, cancer stem cel...

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Bibliographic Details
Main Authors: Qingmei Ye, Xin Zhou, Han Ren, Fangxuan Han, Rong Lin, Juan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
refractory cancers
drug resistance
bufalin
overcome
mechanisms
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1274336/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1274336/full

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