Generalizability of GWA-Identified Genetic Risk Variants for Metabolic Traits to Populations from the Arabian Peninsula

Generalizability of GWA-Identified Genetic Risk Variants for Metabolic Traits to Populations from the Arabian Peninsula

The Arabian Peninsula, located at the nexus of Africa, Europe, and Asia, was implicated in early human migration. The Arab population is characterized by consanguinity and endogamy leading to inbreeding. Global genome-wide association (GWA) studies on metabolic traits under-represent the Arab popula...

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Bibliographic Details
Main Authors: Prashantha Hebbar, Mohamed Abu-Farha, Jehad Abubaker, Arshad Mohamed Channanath, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Genes
Subjects:
risk loci
metabolic traits
GWAS
transferability of risk loci
population diversity
Arab ancestry
Online Access:https://www.mdpi.com/2073-4425/12/10/1637

Internet

https://www.mdpi.com/2073-4425/12/10/1637

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