Pan PPAR agonist stimulation of induced MSCs produces extracellular vesicles with enhanced renoprotective effect for acute kidney injury

Pan PPAR agonist stimulation of induced MSCs produces extracellular vesicles with enhanced renoprotective effect for acute kidney injury

Abstract Background Acute kidney injury (AKI) has a complex pathophysiology and imposes serious health concerns worldwide. Extracellular vesicles (EVs) derived from induced mesenchymal stem cells (iMSCs) have been recognized as novel cell-free therapeutics for various inflammatory and degenerative d...

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Bibliographic Details
Main Authors: Hongduk Kim, Seul Ki Lee, Sungok Hong, Tae Sub Park, Jimin Kim, Soo Kim, Tae Min Kim
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Stem Cell Research & Therapy
Subjects:
Acute kidney injury
Induced mesenchymal stem cells
Priming
Extracellular vesicle
Online Access:https://doi.org/10.1186/s13287-023-03577-0

Internet

https://doi.org/10.1186/s13287-023-03577-0

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