Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study

Bilirubin, an endogenous antioxidant, may play a protective role in cancer development. We applied two-sample Mendelian randomization to investigate whether genetically raised bilirubin levels are causally associated with the risk of ten cancers (pancreas, kidney, endometrium, ovary, breast, prostat...

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Bibliographic Details
Main Authors: Nazlisadat Seyed Khoei, Robert Carreras-Torres, Neil Murphy, Marc J. Gunter, Paul Brennan, Karl Smith-Byrne, Daniela Mariosa, James Mckay, Tracy A. O’Mara, Ruth Jarrett, Henrik Hjalgrim, Karin E. Smedby, Wendy Cozen, Kenan Onel, Arjan Diepstra, Karl-Heinz Wagner, Heinz Freisling
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
bilirubin
UGT1A1
Mendelian randomization
cancer risk
Online Access:https://www.mdpi.com/2073-4409/10/2/394

Internet

https://www.mdpi.com/2073-4409/10/2/394

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