ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane

INPP5E, a phosphoinositide 5-phosphatase, localizes on the ciliary membrane via its C-terminal prenyl moiety, and maintains the distinct ciliary phosphoinositide composition. The ARL3 GTPase contributes to the ciliary membrane localization of INPP5E by stimulating the release of PDE6D bound to preny...

Full description

Bibliographic Details
Main Authors: Sayaka Fujisawa, Hantian Qiu, Shohei Nozaki, Shuhei Chiba, Yohei Katoh, Kazuhisa Nakayama
Format: Article
Language:English
Published: The Company of Biologists 2021-09-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/10/9/bio058843