The nuclear lamina binds the EBV genome during latency and regulates viral gene expression

The Epstein Barr virus (EBV) infects almost 95% of the population worldwide. While typically asymptomatic, EBV latent infection is associated with several malignancies of epithelial and lymphoid origin in immunocompromised individuals. In latently infected cells, the EBV genome persists as a chromat...

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Bibliographic Details
Main Authors: Lisa Beatrice Caruso, Rui Guo, Kelsey Keith, Jozef Madzo, Davide Maestri, Sarah Boyle, Jason Wasserman, Andrew Kossenkov, Benjamin E. Gewurz, Italo Tempera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009669/?tool=EBI