Microbiota and metabolomic profiling coupled with machine learning to identify biomarkers and drug targets in nasopharyngeal carcinoma

Microbiota and metabolomic profiling coupled with machine learning to identify biomarkers and drug targets in nasopharyngeal carcinoma

BackgroundNasopharyngeal carcinoma (NPC) is a prevalent malignancy in certain regions, with radiotherapy as the standard treatment. However, resistance to radiotherapy remains a critical challenge, necessitating the identification of novel biomarkers and therapeutic targets. The tumor-associated mic...

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Bibliographic Details
Main Authors: Junsong Liu, Chongwen Xu, Rui Wang, Jianhua Huang, Ruimin Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
nasopharyngeal carcinoma
radiotherapy resistance
microbiota
Bacteroides acidifaciens
acetate
short-chain fatty acids
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1551411/full

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https://www.frontiersin.org/articles/10.3389/fphar.2025.1551411/full

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