Polymorphism 3435c> t of the ABCB1 gene (rs1045642) does not affect the mirtazapine efficiency and safety profile in patients with depressive disorders comorbid with alcohol use disorder

Background. Mirtazapine is used to treat patients with depressive disorders. A large proportion of patients in this group do not adequately respond to mirtazapine therapy, while many develop undesirable drug reactions of type A. According to the previous studies, P-gp is involved in the biotransform...

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Bibliographic Details
Main Authors: M. S. Zastrozhin, E. A. Grishina, K. A. Ryzhikova, V. Yu. Skryabin, S. G. Koporov, E. A. Bryun, D. A. Sychev
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2021-01-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/4152