Metformin Induces Resistance of Cancer Cells to the Proteasome Inhibitor Bortezomib

The anti-diabetic drug metformin is currently tested for the treatment of hematological and solid cancers. Proteasome inhibitors, e.g., Bortezomib, are approved for the treatment of multiple myeloma and mantle cell lymphoma but are also studied for lung cancer therapy. We here analyzed the interacti...

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Bibliographic Details
Main Authors: Camille Schlesser, Thomas Meul, Georgios Stathopoulos, Silke Meiners
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/6/756