Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes

Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes

Summary: Insulin regulates glucose metabolism through thousands of regulatory mechanisms; however, which regulatory mechanisms are keys to control glucose metabolism remains unknown. Here, we performed kinetic trans-omic analysis by integrating isotope-tracing glucose flux and phosphoproteomic data...

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Bibliographic Details
Main Authors: Satoshi Ohno, Lake-Ee Quek, James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Tomoyoshi Soga, David E. James, Shinya Kuroda
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Biological Sciences
Mathematical Biosciences
Systems Biology
Proteomics
Metabolomics
Metabolic Flux Analyisis
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306714

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http://www.sciencedirect.com/science/article/pii/S2589004220306714

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