Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate

Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate

Summary: In higher vertebrates, cephalic neural crest cells (NCCs) form craniofacial skeleton by differentiating into chondrocytes and osteoblasts. A subpopulation of cephalic NCCs, cardiac NCCs (CNCCs), migrates to the heart. However, CNCCs mostly do not yield skeletogenic derivatives, and the mole...

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Main Authors: Hiroyuki N. Arai, Fuminori Sato, Takuya Yamamoto, Knut Woltjen, Hiroshi Kiyonari, Yuki Yoshimoto, Chisa Shukunami, Haruhiko Akiyama, Ralf Kist, Atsuko Sehara-Fujisawa
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719311969

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http://www.sciencedirect.com/science/article/pii/S2211124719311969

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