Tanshinone IIA attenuates valvular interstitial cells’ calcification induced by oxidized low density lipoprotein via reducing endoplasmic reticulum stress

Tanshinone IIA attenuates valvular interstitial cells’ calcification induced by oxidized low density lipoprotein via reducing endoplasmic reticulum stress

Recent studies revealed that endoplasmic reticulum (ER) stress played an emerging role of in valve calcification. Tanshinone IIA (TanIIA) has been a research hotspot in cardiovascular diseases. Previously we found that sodium TanIIA dampened the pathological phenotype transition of valvular intersti...

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Bibliographic Details
Main Authors: Chen Fang, Yang Dongqiang, Ru Yuhua, Bai Yu, Pei Xueliang, Sun Jie, Cao Shan, Wang Weiguang, Gao Aishe
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Open Medicine
Subjects:
tanshinone iia
osteoblastic differentiation
er stress
valvular interstitial cells
Online Access:https://doi.org/10.1515/med-2023-0797

Internet

https://doi.org/10.1515/med-2023-0797

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