An inhibitor/anti-inhibitor system controls the activity of lytic transglycosylase MltF in Pseudomonas aeruginosa

ABSTRACTMost bacterial cell envelopes contain a cell wall layer made of peptidoglycan. The synthesis of new peptidoglycan is critical for cell growth, division, and morphogenesis and is also coordinated with peptidoglycan hydrolysis to accommodate the new material. However, the enzymes that cleave p...

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Bibliographic Details
Main Authors: Michelle Wang, Sheya Xiao Ma, Andrew J. Darwin
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02022-23