Dynamic evaluation of blood immune cells predictive of response to immune checkpoint inhibitors in NSCLC by multicolor spectrum flow cytometry

Dynamic evaluation of blood immune cells predictive of response to immune checkpoint inhibitors in NSCLC by multicolor spectrum flow cytometry

IntroductionImmune checkpoint inhibitors (ICIs) only benefit a subset of cancer patients, underlining the need for predictive biomarkers for patient selection. Given the limitations of tumor tissue availability, flow cytometry of peripheral blood mononuclear cells (PBMCs) is considered a noninvasive...

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Bibliographic Details
Main Authors: Weijie Ma, Sixi Wei, Siqi Long, Eddie C. Tian, Bridget McLaughlin, Maria Jaimes, Dennis J. Montoya, Varun R. Viswanath, Jeremy Chien, Qianjun Zhang, Jonathan E. Van Dyke, Shuai Chen, Tianhong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
immune biomarker
blood
predictive
multiplex
peripheral blood mononuclear cells
immune checkpoint inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1206631/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1206631/full

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