Trans, trans-2,4-decadienal impairs vascular endothelial function by inducing oxidative/nitrative stress and apoptosis

Trans, trans-2,4-decadienal impairs vascular endothelial function by inducing oxidative/nitrative stress and apoptosis

Aldehydes are implicated in the development of hypertension. Trans, trans-2,4-decadienal (tt-DDE), a dietary α,β-unsaturated aldehyde, is widespread in many food products. However, the role of tt-DDE in the pathophysiology of hypertension remains unknown. This study was designed to investigate wheth...

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Bibliographic Details
Main Authors: Yuanyuan Hu, Fawen Yin, Zhenlong Yu, Yulin Peng, Guanhua Zhao, Zhongyuan Liu, Dayong Zhou, Xiaochi Ma, Fereidoon Shahidi, Beiwei Zhu
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Trans
trans-2,4-decadienal
Blood pressure
Endothelial dysfunction
Oxidative stress
Nitrative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720304225

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http://www.sciencedirect.com/science/article/pii/S2213231720304225

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