A novel gene functional similarity calculation model by utilizing the specificity of terms and relationships in gene ontology
Abstract Background Recently, with the foundation and development of gene ontology (GO) resources, numerous works have been proposed to compute functional similarity of genes and achieved series of successes in some research fields. Focusing on the calculation of the information content (IC) of term...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-022-04557-6 |