Temporal changes in glucose metabolism reflect polarization in resident and monocyte-derived macrophages after myocardial infarction

Temporal changes in glucose metabolism reflect polarization in resident and monocyte-derived macrophages after myocardial infarction

IntroductionMetabolic reprogramming from glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle and oxidative phosphorylation may mediate macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype. We hypothesized that changes in cardiac macrophage glucose met...

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Bibliographic Details
Main Authors: Alan J. Mouton, Nikaela M. Aitken, Sydney P. Moak, Jussara M. do Carmo, Alexandre A. da Silva, Ana C. M. Omoto, Xuan Li, Zhen Wang, Alexandra C. Schrimpe-Rutledge, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, John E. Hall
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
glycolysis
immunometabolism
macrophage
inflammation
heart failure
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1136252/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2023.1136252/full

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