The Immunomodulatory Signature of Extracellular Vesicles From Cardiosphere-Derived Cells: A Proteomic and miRNA Profiling

The Immunomodulatory Signature of Extracellular Vesicles From Cardiosphere-Derived Cells: A Proteomic and miRNA Profiling

Experimental data demonstrated that the regenerative potential and immunomodulatory capacity of cardiosphere-derived cells (CDCs) is mediated by paracrine mechanisms. In this process, extracellular vesicles derived from CDCs (EV-CDCs) are key mediators of their therapeutic effect. Considering the fu...

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Bibliographic Details
Main Authors: Esther López, Federica Marinaro, María de los Ángeles de Pedro, Francisco Miguel Sánchez-Margallo, María Gómez-Serrano, Viviane Ponath, Elke Pogge von Strandmann, Inmaculada Jorge, Jesús Vázquez, Luis Miguel Fernández-Pereira, Verónica Crisóstomo, Verónica Álvarez, Javier G. Casado
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cardiosphere-derived cells
cardiac stem cells
proteomic analyses
quantitative polymerase chain reaction
interferon-γ
extracellular vesicles
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00321/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00321/full

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