The sphingosine-1-phosphate/RhoA/Rho associated kinases/myosin light chain pathway in detrusor of female rats is down-regulated in response to ovariectomy

Abstract. Background. Dysuria is one of the main symptoms of genitourinary syndrome of menopause, which causes serious disruption to the normal life of peri-menopausal women. Studies have shown that it is related to decrease of detrusor contractile function, but the exact mechanism is still poorly u...

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Bibliographic Details
Main Authors: Wei Zhang, Xiao-Dong Liu, Jia-Wen Wang, Ling-Feng Meng, Yao-Guang Zhang, Jian-Ye Wang, Yuan-Yuan Ji
Format: Article
Language:English
Published: Wolters Kluwer 2020-05-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000767