Diabetic Retinopathy and Regulation of Mitochondrial Glutathione–Glutathione Peroxidase Axis in Hyperhomocysteinemia

Diabetic patients have elevated homocysteine levels, and hyperhomocysteinemia is shown to exacerbate mitochondrial damage, which plays a central role in diabetic retinopathy. Glutathione peroxidases (GPx) catalyze hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) reduction using...

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Bibliographic Details
Main Authors: Pooja Malaviya, Renu A. Kowluru
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/13/3/254