Effects of Sparassis latifolia neutral polysaccharide on immune activity via TLR4-mediated MyD88-dependent and independent signaling pathways in RAW264.7 macrophages

Effects of Sparassis latifolia neutral polysaccharide on immune activity via TLR4-mediated MyD88-dependent and independent signaling pathways in RAW264.7 macrophages

BackgroundSparassis latifolia (S. latifolia) is a precious edible fungus with multiple biological activities. To date, no study has been investigated the underlying molecular mechanism of immunoregulation caused by the neutral polysaccharide of S. latifolia.Materials and methodsTo investigate immuno...

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Bibliographic Details
Main Authors: Zening Qiao, Yue Zhao, Menghao Wang, Jinling Cao, Mingchang Chang, Shaojun Yun, Yanfen Cheng, Feier Cheng, Cuiping Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Nutrition
Subjects:
Sparassis latifolia
neutral polysaccharide
macrophage RAW264.7
immune activity
toll-like receptor-4
MyD88 signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.994971/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.994971/full

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