Cytolethal distending toxin B inoculation leads to distinct gut microtypes and IBS-D-like microRNA-mediated gene expression changes in a rodent model

Cytolethal distending toxin B inoculation leads to distinct gut microtypes and IBS-D-like microRNA-mediated gene expression changes in a rodent model

ABSTRACTDiarrhea-predominant irritable bowel syndrome (IBS-D), associated with increased intestinal permeability, inflammation, and small intestinal bacterial overgrowth, can be triggered by acute gastroenteritis. Cytolethal distending toxin B (CdtB) is produced by gastroenteritis-causing pathogens...

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Bibliographic Details
Main Authors: Gabriela Leite, Juliana de Freitas Germano, Walter Morales, Stacy Weitsman, Gillian M Barlow, Gonzalo Parodi, Maya L Pimentel, Maria Jesus Villanueva-Millan, Maritza Sanchez, Sarah Ayyad, Ali Rezaie, Ruchi Mathur, Mark Pimentel
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
Irritable bowel syndrome
cytolethal distending toxin
gut microbiome
host gene expression
microRNAs
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2293170

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2293170

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