Negative Modulation of the Metabotropic Glutamate Receptor Type 5 as a Potential Therapeutic Strategy in Obesity and Binge-Like Eating Behavior

Negative Modulation of the Metabotropic Glutamate Receptor Type 5 as a Potential Therapeutic Strategy in Obesity and Binge-Like Eating Behavior

Obesity is a multifactorial disease, which in turn contributes to the onset of comorbidities, such as diabetes and atherosclerosis. Moreover, there are only few options available for treating obesity, and most current pharmacotherapy causes severe adverse effects, while offering minimal weight loss....

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Bibliographic Details
Main Authors: Tadeu P. D. Oliveira, Bruno D. C. Gonçalves, Bruna S. Oliveira, Antonio Carlos P. de Oliveira, Helton J. Reis, Claudia N. Ferreira, Daniele C. Aguiar, Aline S. de Miranda, Fabiola M. Ribeiro, Erica M. L. Vieira, András Palotás, Luciene B. Vieira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
obesity
mGluR5
high-fat
inflammation
glutamate
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.631311/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.631311/full

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