Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish

Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish

Background: 20(S)-Protopanaxadiol 20-O-D-glucopyranoside, also called compound K (CK), exerts antidiabetic effects that are mediated by insulin secretion through adenosine triphosphate (ATP)-sensitive potassium (KATP) channels in pancreatic β-cells. However, the antidiabetic effects of CK may be lim...

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Bibliographic Details
Main Authors: Youn Hee Nam, Hoa Thi Le, Isabel Rodriguez, Eun Young Kim, Keonwoo Kim, Seo Yule Jeong, Sang Ho Woo, Yeong Ro Lee, Rodrigo Castañeda, Jineui Hong, Min Gun Ji, Ung-Jin Kim, Bin Na Hong, Tae Woo Kim, Tong Ho Kang
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Ginseng Research
Subjects:
β-cyclodextrin
adenosine triphosphate-sensitive potassium blocker
compound K
pancreatic islet
zebrafish larva
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845316301166

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http://www.sciencedirect.com/science/article/pii/S1226845316301166

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