Synovial fluid CD69+CD8+ T cells with tissue‐resident phenotype mediate perforin‐dependent citrullination in rheumatoid arthritis

Abstract Objectives Although the importance of tissue‐resident memory T (TRM) cells in organ‐specific chronic inflammation has been recognised, little is known about their role in rheumatoid arthritis (RA). Here, we examined the characteristics of synovial fluid CD8+ T cells that express canonical T...

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Bibliographic Details
Main Authors: Jae Hyung Jung, Jung Sun Lee, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Eui‐Cheol Shin, Seokchan Hong
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
Online Access:https://doi.org/10.1002/cti2.1140