Design, Physicochemical Characterization, and In Vitro Permeation of Innovative Resatorvid Topical Formulations for Targeted Skin Drug Delivery

Design, Physicochemical Characterization, and In Vitro Permeation of Innovative Resatorvid Topical Formulations for Targeted Skin Drug Delivery

Nonmelanoma skin cancers (NMSCs) are the most common malignancies worldwide and affect more than 5 million people in the United States every year. NMSC is directly linked to the excessive exposure of the skin to solar ultraviolet (UV) rays. The toll-like receptor 4 (TLR4) antagonist, resatorvid (TAK...

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Bibliographic Details
Main Authors: Victor H. Ruiz, David Encinas-Basurto, Bo Sun, Basanth Babu Eedara, Sally E. Dickinson, Georg T. Wondrak, H. -H. Sherry Chow, Clara Curiel-Lewandrowski, Heidi M. Mansour
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
resatorvid (TAK-242)
nonmelanoma skin cancers
topical drug delivery
HaCaT human skin cell line
NHEK normal primary human skin cells
Strat-M synthetic membrane
Online Access:https://www.mdpi.com/1999-4923/14/4/700

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https://www.mdpi.com/1999-4923/14/4/700

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