Custodiol<sup>®</sup> Supplemented with Synthetic Human Relaxin Decreases Ischemia-Reperfusion Injury after Porcine Kidney Transplantation

Custodiol<sup>®</sup> Supplemented with Synthetic Human Relaxin Decreases Ischemia-Reperfusion Injury after Porcine Kidney Transplantation

<b>Objective.</b> Ischemia-reperfusion injury (IRI) is inevitable after kidney transplantation (KT), impairing outcomes. Relaxin-2 (RLX) is a promising insulin-related peptide hormone that protects against renal IRI in rodents, although large animal models are needed before RLX can be te...

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Bibliographic Details
Main Authors: Augustinas Bausys, Juste Maneikyte, Bettina Leber, Jennifer Weber, Nicole Feldbacher, Kestutis Strupas, Thomas Bernd Dschietzig, Peter Schemmer, Philipp Stiegler
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
relaxin
kidney transplantation
apoptosis
ischemia-reperfusion injury
static cold storage
Online Access:https://www.mdpi.com/1422-0067/22/21/11417

Internet

https://www.mdpi.com/1422-0067/22/21/11417

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