MexY-Promoted Aminoglycoside Resistance in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>: Involvement of a Putative Proximal Binding Pocket in Aminoglycoside Recognition
ABSTRACT The resistance-nodulation-division (RND) family multidrug efflux system MexXY-OprM is a major determinant of aminoglycoside resistance in Pseudomonas aeruginosa, although the details of aminoglycoside recognition and export by MexY, the substrate-binding RND component of this efflux system,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2014-05-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.01068-14 |