Azeliragon ameliorates Alzheimer's disease via the Janus tyrosine kinase and signal transducer and activator of transcription signaling pathway

OBJECTIVES: TTP488, an antagonist of the receptor for advanced glycation end-products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer’s disease (AD). However, the mechanism underlying the protective action of TTP488 against AD has not yet been fully explored. ME...

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Bibliographic Details
Main Authors: Lijuan Yang, Yepei Liu, Yuanyuan Wang, Junsheng Li, Na Liu
Format: Article
Language:English
Published: Elsevier España
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/pdf/clin/v76/1807-5932-clin-76-e2348.pdf