Conversion to mTOR-inhibitors with calcineurin inhibitor elimination or minimization reduces urinary polyomavirus BK load in kidney transplant recipients

Polyomavirus BK (BKV) reactivation causes allograft dysfunction in some kidney transplant recipients. The use of mammalian target of rapamycin (mTOR) inhibitor-based immunotherapy is associated with a lower incidence of polyomavirus-associated nephropathy compared with other immunosuppressants. This...

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Bibliographic Details
Main Authors: Chieh-Li Yen, Ya-Chung Tian, Hsin-Hsu Wu, Cheng-Hao Weng, Yung-Chang Chen, Kun-Hua Tu, Shou-Hsuan Liu, Cheng-Chia Lee, Ping-Chin Lai, Ji-Tseng Fang, Cheng-Chieh Hung, Chih-Wei Yang, Yi-Jung Li
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664616000498