Synthesis and Antiplasmodial Activity of Bisindolylcyclobutenediones

Synthesis and Antiplasmodial Activity of Bisindolylcyclobutenediones

Malaria is one of the most dangerous infectious diseases. Because the causative <i>Plasmodium</i> parasites have developed resistances against virtually all established antimalarial drugs, novel antiplasmodial agents are required. In order to target plasmodial kinases, novel <i>N&l...

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Bibliographic Details
Main Authors: Duc Hoàng Lande, Abed Nasereddin, Arne Alder, Tim W. Gilberger, Ron Dzikowski, Johann Grünefeld, Conrad Kunick
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
bisindolylmaleimide
cyclobutenedione
drug design
drug screening
Friedel-Crafts reaction
glycogen synthase kinase-3
Online Access:https://www.mdpi.com/1420-3049/26/16/4739

Internet

https://www.mdpi.com/1420-3049/26/16/4739

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