Cationic Mechanosensitive Channels Mediate Trabecular Meshwork Responses to Cyclic Mechanical Stretch

Cationic Mechanosensitive Channels Mediate Trabecular Meshwork Responses to Cyclic Mechanical Stretch

The trabecular meshwork (TM) is responsible for intraocular pressure (IOP) homeostasis in the eye. The tissue senses IOP fluctuations and dynamically adapts to the mechanical changes to either increase or decrease aqueous humor outflow. Cationic mechanosensitive channels (CMCs) have been reported to...

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Bibliographic Details
Main Authors: Susu Chen, Wenyan Wang, Qilong Cao, Shen Wu, Ningli Wang, Lixia Ji, Wei Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
trabecular meshwork
cationic mechanosensitive channels
mechanical stretching
proteomics analysis
IOP homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.881286/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.881286/full

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