Pharmacogenetic testing of allelic variants of the CYP2D6 gene in hormone positive breast cancer
Tamoxifen is the drug of choice for endocrine therapy of hormone receptor- positive breast cancer in women in the reproductive period. The metabolic activity of tamoxifen is determined by the activity of the enzyme CYP2D6, encoded by the gene of the same name: under the action of the enzyme, tamox...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
ABV-press
2017-10-01
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Series: | Успехи молекулярной онкологии |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/102 |