Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysis

Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysis

BackgroundObservational studies have indicated associations between type 2 diabetes mellitus (T2DM) and both colorectal cancer (CRC) and inflammatory bowel disease (IBD). However, the underlying causality and biological mechanisms between these associations remains unclear.MethodsWe conducted a bidi...

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Bibliographic Details
Main Authors: Xiang Xiao, Xuanyu Wu, Lu Yi, Fengming You, Xueke Li, Chong Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Endocrinology
Subjects:
type 2 diabetes mellitus
colorectal cancer
inflammatory bowel disease
Crohn’s disease
ulcerative colitis
single nucleotide polymorphisms
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1275699/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1275699/full

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