Informed interpretation of metagenomic data by StrainPhlAn enables strain retention analyses of the upper airway microbiome

Informed interpretation of metagenomic data by StrainPhlAn enables strain retention analyses of the upper airway microbiome

ABSTRACTShotgun metagenomic sequencing has the potential to provide bacterial strain-level resolution which is of key importance to tackle a host of clinical questions. While bioinformatic tools that achieve strain-level resolution are available, thorough benchmarking is needed to validate their use...

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Bibliographic Details
Main Authors: Nadja Mostacci, Tsering Monika Wüthrich, Léa Siegwald, Silas Kieser, Ruth Steinberg, Olga Sakwinska, Philipp Latzin, Insa Korten, Markus Hilty
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSystems
Subjects:
respiratory tract
metagenomics
bacterial culture
strain resolution
genome analysis
Online Access:https://journals.asm.org/doi/10.1128/msystems.00724-23

Internet

https://journals.asm.org/doi/10.1128/msystems.00724-23

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