A<sub>2B</sub> Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia: New Insights into MRP3 Transporter Function

A<sub>2B</sub> Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia: New Insights into MRP3 Transporter Function

Glioblastoma is the most common and aggressive primary brain tumor, characterized by its high chemoresistance and the presence of a cell subpopulation that persists under hypoxic niches, called glioblastoma stem-like cells (GSCs). The chemoresistance of GSCs is mediated in part by adenosine signalin...

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Bibliographic Details
Main Authors: José-Dellis Rocha, Daniel Uribe, Javiera Delgado, Ignacio Niechi, Sebastián Alarcón, José Ignacio Erices, Rómulo Melo, Rodrigo Fernández-Gajardo, Flavio Salazar-Onfray, Rody San Martín, Claudia Quezada Monrás
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
MRP3
adenosine
A<sub>2B</sub>
glioblastoma
chemoresistance
GSCs
Online Access:https://www.mdpi.com/1422-0067/23/16/9022

Internet

https://www.mdpi.com/1422-0067/23/16/9022

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