Unbiased immunome characterisation correlates with COVID-19 mRNA vaccine failure in immunocompromised adults

Unbiased immunome characterisation correlates with COVID-19 mRNA vaccine failure in immunocompromised adults

IntroductionCoronavirus disease 2019 (COVID-19) affects the population unequally, with a greater impact on older and immunosuppressed people.MethodsHence, we performed a prospective experimental cohort study to characterise the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) v...

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Main Authors: Juan H-Vázquez, Paloma Cal-Sabater, Elisa Arribas-Rodríguez, Aida Fiz-López, Candido Perez-Segurado, Álvaro Martín-Muñoz, Ángel De Prado, Marina Perez Mazzali, Carolina G. de Castro, Alejandro G. del Hierro, Ignacio de la Fuente Graciani, Sonia Pérez González, Sara Gutiérrez, Pablo Tellería, Cristina Novoa, Silvia Rojo Rello, Antonio Garcia-Blesa, Rosa Sedano, Ana María Martínez García, Sonsoles Garcinuño Pérez, Marta Domínguez-Gil, Cristina Hernán García, Ma Mercedes Guerra, Eduardo Muñoz-Sánchez, Cristina Barragan-Pérez, Soraya Diez Morales, Oriana Casazza Donnarumma, Daniel Ramos Pollo, Natalia Santamarta Solla, Paula Ma Álvarez Manzanares, Sara Bravo, Cristina García Alonso, Luis Alberto Avendaño Fernández, Jenifer Gay Alonso, José A. Garrote, Eduardo Arranz, José María Eiros, Fernando Rescalvo Santiago, Carolina Quevedo Villegas, Eduardo Tamayo, Antonio Orduña, Carlos Dueñas, María Jesús Peñarrubia, Sara Cuesta-Sancho, María Montoya, David Bernardo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
computational cytometry
vaccine failure
COVID-19
immunome
immunocompromised adult
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1405217/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1405217/full

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