Multiplex Epstein-Barr virus BALF2 genotyping detects high-risk variants in plasma for population screening of nasopharyngeal carcinoma

Multiplex Epstein-Barr virus BALF2 genotyping detects high-risk variants in plasma for population screening of nasopharyngeal carcinoma

Abstract Background Epstein-Barr Virus (EBV)-associated nasopharyngeal carcinoma (NPC) exhibits unusual geographic restriction despite ubiquitous lifelong infection. Screening programs can detect most NPC cases at an early stage, but existing EBV diagnostics are limited by false positives and low po...

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Bibliographic Details
Main Authors: Jacob A. Miller, Malaya K. Sahoo, Fumiko Yamamoto, ChunHong Huang, Hannah Wang, James L. Zehnder, Quynh-Thu Le, Benjamin A. Pinsky
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Molecular Cancer
Subjects:
Nasopharyngeal carcinoma
Epstein-Barr virus
Cancer screening
Plasma
BALF2
Cost-effectiveness
Online Access:https://doi.org/10.1186/s12943-022-01625-6

Internet

https://doi.org/10.1186/s12943-022-01625-6

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