Optical Imaging of Cancer-Related Proteases Using Near-Infrared Fluorescence Matrix Metalloproteinase-Sensitive and Cathepsin B-Sensitive Probes

<p>Cathepsin B and matrix metalloproteinase (MMP) play key roles in tumor progression by controlled degradation of extracellular matrix. Consequently, these proteases have been attracted in cancer research, and many imaging probes utilizing these proteases have been developed. Our groups devel...

Full description

Bibliographic Details
Main Author: Ji Young Yhee, Sun Ah Kim, Heebeom Koo, Sohee Son, Ju Hee Ryu, In-Chan Youn, Kuiwon Choi, Ick Chan Kwon, Kwangmeyung Kim
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Theranostics
Online Access:http://www.thno.org/v02p0179.htm