Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations
Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-05-01
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Series: | Annals of Human Biology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/03014460.2022.2100477 |