Multiplex Identification of Antigen-Specific T Cell Receptors Using a Combination of Immune Assays and Immune Receptor Sequencing.

Multiplex Identification of Antigen-Specific T Cell Receptors Using a Combination of Immune Assays and Immune Receptor Sequencing.

Monitoring antigen-specific T cells is critical for the study of immune responses and development of biomarkers and immunotherapeutics. We developed a novel multiplex assay that combines conventional immune monitoring techniques and immune receptor repertoire sequencing to enable identification of T...

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Bibliographic Details
Main Authors: Mark Klinger, Francois Pepin, Jen Wilkins, Thomas Asbury, Tobias Wittkop, Jianbiao Zheng, Martin Moorhead, Malek Faham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4624875?pdf=render

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http://europepmc.org/articles/PMC4624875?pdf=render

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