Parenteral Lipid-Based Nanoparticles for CNS Disorders: Integrating Various Facets of Preclinical Evaluation towards More Effective Clinical Translation

Parenteral Lipid-Based Nanoparticles for CNS Disorders: Integrating Various Facets of Preclinical Evaluation towards More Effective Clinical Translation

Contemporary trends in combinatorial chemistry and the design of pharmaceuticals targeting brain disorders have favored the development of drug candidates with increased lipophilicity and poorer water solubility, with the expected improvement in delivery across the blood–brain barrier (BBB). The gro...

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Bibliographic Details
Main Authors: Tanja Ilić, Jelena B. Đoković, Ines Nikolić, Jelena R. Mitrović, Ivana Pantelić, Snežana D. Savić, Miroslav M. Savić
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
liposomes
nanoemulsions
solid lipid nanoparticles
nanostructured lipid carriers
blood–brain barrier
brain targeting ligands
Online Access:https://www.mdpi.com/1999-4923/15/2/443

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https://www.mdpi.com/1999-4923/15/2/443

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