Membrane Topology Mapping of the O-Antigen Flippase (Wzx), Polymerase (Wzy), and Ligase (WaaL) from <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> PAO1 Reveals Novel Domain Architectures
ABSTRACT Biosynthesis of B-band lipopolysaccharide (LPS) in Pseudomonas aeruginosa follows the Wzy-dependent pathway, requiring the integral inner membrane proteins Wzx (O-antigen [O-Ag] flippase), Wzy (O-Ag polymerase), and WaaL (O-Ag ligase). For an important first step in deciphering the mechanis...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2010-08-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.00189-10 |