Promoter Sequence of Shiga Toxin 2 (Stx2) Is Recognized <italic toggle="yes">In Vivo</italic>, Leading to Production of Biologically Active Stx2

ABSTRACT Shiga toxins (Stx) are the main agent responsible for the development of hemolytic-uremic syndrome (HUS), the most severe and life-threatening systemic complication of infection with enterohemorrhagic Escherichia coli (EHEC) strains. We previously described Stx2 expression by eukaryotic cel...

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Main Authors: Leticia V. Bentancor, Maria P. Mejías, Alípio Pinto, Marcos F. Bilen, Roberto Meiss, Maria C. Rodriguez-Galán, Natalia Baez, Luciano P. Pedrotti, Jorge Goldstein, Pablo D. Ghiringhelli, Marina S. Palermo
Format: Article
Language:English
Published: American Society for Microbiology 2013-11-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00501-13