Design Space Approach for the Optimization of Green Fluidized Bed Granulation Process in the Granulation of a Poorly Water-Soluble Fenofibrate Using Design of Experiment

Design Space Approach for the Optimization of Green Fluidized Bed Granulation Process in the Granulation of a Poorly Water-Soluble Fenofibrate Using Design of Experiment

In the pharmaceutical industry, the systematic optimization of process variables using a quality-by-design (QbD) approach is highly precise, economic and ensures product quality. The current research presents the implementation of a design-of-experiment (DoE) driven QbD approach for the optimization...

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Bibliographic Details
Main Authors: Mohamed H. Fayed, Ahmed Alalaiwe, Ziyad S. Almalki, Doaa A. Helal
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
green fluidized bed granulation
design space
quality-by-design
design-of-experiment
granules and tablets
Online Access:https://www.mdpi.com/1999-4923/14/7/1471

Internet

https://www.mdpi.com/1999-4923/14/7/1471

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