Molecular Characterization of Cancer Associated Fibroblasts in Prostate Cancer

Molecular Characterization of Cancer Associated Fibroblasts in Prostate Cancer

Background: Stromal components surrounding epithelial cancer cells seem to play a pivotal role during epithelial-to-mesenchymal transition (EMT), tumor invasion, and metastases. To identify the molecular mechanisms underlying tumor–stroma interactions may yield novel therapeutic targets for prostate...

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Bibliographic Details
Main Authors: Giovanni Vitale, Michele Caraglia, Volker Jung, Jörn Kamradt, Davide Gentilini, Maria Teresa Di Martino, Alessandra Dicitore, Marianna Abate, Pierosandro Tagliaferri, Annalisa Itro, Matteo Ferro, Raffaele Balsamo, Marco De Sio, Gaetano Facchini, Luca Persani, Kai Schmitt, Matthias Saar, Michael Stöckle, Gerhard Unteregger, Silvia Zappavigna
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
androgen signaling
cancer-associated fibroblasts
cell proliferation
non cancer-associated fibroblasts
prostate cancer
transcriptomic profiling
Online Access:https://www.mdpi.com/2072-6694/14/12/2943

Internet

https://www.mdpi.com/2072-6694/14/12/2943

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