Hydrocephalus in <i>Nfix<sup>−/−</sup></i> Mice Is Underpinned by Changes in Ependymal Cell Physiology

Hydrocephalus in <i>Nfix<sup>−/−</sup></i> Mice Is Underpinned by Changes in Ependymal Cell Physiology

Nuclear factor one X (NFIX) is a transcription factor required for normal ependymal development. Constitutive loss of <i>Nfix</i> in mice (<i>Nfix<sup>−/−</sup></i>) is associated with hydrocephalus and sloughing of the dorsal ependyma within the lateral ventricle...

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Bibliographic Details
Main Authors: Danyon Harkins, Tracey J. Harvey, Cooper Atterton, Ingrid Miller, Laura Currey, Sabrina Oishi, Maria Kasherman, Raul Ayala Davila, Lucy Harris, Kathryn Green, Hannah Piper, Robert G. Parton, Stefan Thor, Helen M. Cooper, Michael Piper
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
ependymal cells
cell morphology
adherens junctions
cilia
hydrocephalus
epithelial adhesion
Online Access:https://www.mdpi.com/2073-4409/11/15/2377

Internet

https://www.mdpi.com/2073-4409/11/15/2377

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